Betting

10/10/24

5 min read

5 Best PrizePicks More-Less Picks To Smash in NFL Week 6

Oct 6, 2024; Santa Clara, California, USA; San Francisco 49ers tight end George Kittle (85) gestures after a catch against the Arizona Cardinals during the fourth quarter at Levi's Stadium. Mandatory Credit: Darren Yamashita-Imagn Images

With five weeks of data from the 2024 season, there's a bit more research for some PrizePicks more-less picks to make for Week 6.

This week's slate of games includes a divisional Thursday night matchup between the San Francisco 49ers and Seattle Seahawks and a battle near the top of the NFC between the Dallas Cowboys and Detroit Lions. However, one of the most intriguing matchups will be a Lamar Jackson and Jayden Daniels showdown as the two dual-threat quarterbacks go head-to-head for the first time.

With so many games to watch and players to monitor, here are our five best PrizePicks more-less picks to choose from for Week 6.

George Kittle 4 Receptions: More

There isn't a better tight end in the NFL than George Kittle.

Kittle has missed one game so far, but in every game that he's played, he's had at least four receptions. Last week was his most productive game of the year, catching 8-of-12 targets for 64 yards and a touchdown.

On the other hand, the Seattle Seahawks defense lacks the linebackers to handle a player like Kittle in coverage. They rank 23rd by defensive DVOA when covering tight ends but have only played one true impact player at the position, Sam LaPorta.

Expect Brock Purdy to keep targeting Kittle on Thursday night.


Philadelphia Eagles running back Saquon Barkley (26) runs during the first half against the Green Bay Packers at Neo Quimica Arena. Kirby Lee-Imagn Images.

Saquon Barkley 83.5 Rushing Yards: Less

There might be too many mouths to feed for the Philadelphia Eagles this week, but their fans will not be complaining.

In their first practice following their bye week, both star wide receivers, A.J. Brown and DeVonta Smith, were full participants. Those are some much-needed reinforcements for a passing game that had been without both of its top weapons.

Saquon Barkley should still have a productive outing. He's had more than 100 yards twice and has surpassed that 83.5-yard number in all of his games. He's one of the most productive and elusive running backs in the league, so it's not like he's going to be completely shut down.

However, since Brown and Smith are healthy, the Eagles should be focused on getting those two back on track, which could limit Barkley's opportunities.


Chicago Bears quarterback Caleb Williams (18) greets fans after the second half against the Los Angeles Rams at Soldier Field. Matt Marton-Imagn Images.

Caleb Williams 235.5 Passing Yards: More

It looks like Caleb Williams is finally starting to find his footing.

The No. 1 overall pick by the Chicago Bears had the first 300-yard game of his career last week against the Carolina Panthers. He threw for 304 yards, two touchdowns, and zero interceptions while finally connecting on multiple deep balls down the field.

Williams should have another opportunity to surpass 300 passing yards against a porous Jacksonville Jaguars defense that was gashed by Joe Flacco and the Indianapolis Colts last week. In fact, the Jaguars defense ranks last in the NFL by DVOA.

That's the perfect opportunity for Williams to keep his hot streak rolling.


Tennessee Titans wide receiver DeAndre Hopkins (10) attempts to make a catch behind Miami Dolphins cornerback Kader Kohou (4) during the first half at Hard Rock Stadium. Jasen Vinlove-Imagn Images.

DeAndre Hopkins 40.5 Receiving Yards: Less

It seems like DeAndre Hopkins may not be in Tennessee much longer.

The former superstar wideout is having an outright terrible start to 2024. Through four games, he's caught just 10 passes for 121 yards and one touchdown. If he stays healthy the whole year, he'd surpass just over 500 receiving yards at his current pace for the entire season.

Taking out his solid Week 3 performance against the Green Bay Packers, Hopkins has just four catches for 48 yards in three games.

Hopkins can bounce back after the bye week with a game against the divisional rival Indianapolis Colts. They don't have a great defense, but CB Jaylon Jones is starting to emerge as a legitimate starter with two interceptions and six pass breakups. He also has the size at 6-foot-2 to be a strong matchup against Hopkins.

Unless the Titans figured out their offense during the bye week, don't expect a heavy workload from Hopkins in Week 6.


New England Patriots quarterback Drake Maye (10) throws the ball before a game against the Miami Dolphins at Gillette Stadium. Brian Fluharty-Imagn Images

DRake Maye 29.5 Pass Attempts: More

The New England Patriots are taking their Ferrari out of the garage for the first time. They might as well make the most of it.

Head coach Jerod Mayo announced that Drake Maye would be taking over as the starting quarterback in Week 6. It might not be pretty for the No. 3 overall pick because Jacoby Brissett was the third-most pressured quarterback in the league before being benched.

Even if Maye constantly throws while under duress, he'll likely have to air it out a lot to keep the Patriots alive. The Patriots are seven-point underdogs, and that means that they will likely play from a negative game script for the majority of the contest.

Mayo and the coaching staff may want to get the run game going to keep Maye from getting knocked around. However, if they're serious about competing in this game, they need their first-round rookie quarterback to air it out a bit.


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